Who is Most At-Risk for Overdose?
Patient >
Prior opioid overdose
Recreational opioid use
Mental health disorders
Untreated sleep disorders
Lung disease
Kidney or liver problems
Population >
Middle-aged adults
More men than women
Whites and American Indian or Alaska Natives
People in rural areas
Residents of states with higher sales and non-medical use of prescription painkillers
Medication >
Starting or switching to new opioids
Extended-release or long-acting opioid
Resumption of opioid therapy after period of abstinence
Morphine Equivalent Dose (MED) greater than 50 or aggressive dose increases
Multiple prescriptions or prescribers
Route of administration (injectables)
Concurrent Central Nervous System (CNS) depressants prescribed